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K. Inoue, G. Tomita, M. Wakakura, J. Inoue; Comparison of Sensitivity inGlaucoma Detection BetweenTwo Diagnostic Programs in Scanning Laser Tomography . Invest. Ophthalmol. Vis. Sci. 2004;45(13):3321.
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Purpose: To compare the sensitivity in glaucoma detection between Moorfield regression classification (Moorfield) and FSM discriminant function values (FSM) built–in Heidelberg Retina Tomograph–2 (HRT). Methods: One hundred eyes from 100 Japanese subjects with primary open–angle glaucoma, aged 54.0 + 12.5 yrs (mean + SD), refractive errors within + 5 D, and mild glaucomatous defects corresponding funduscopically identified optic disc damages (within – 15 dB of mean deviation) by the program SITA 30–2 of Humphrey visual field, were enrolled in the study. The optic disc imaging and analyses by HRT were performed by one experienced examiner. When the Moorfield scored ‘outside normal limits’, or the FSM showed less than 0 value, it was counted as a glaucomatous abnormal disc. Results: Of all the sensitivity of glaucoma detection was 68 eyes (68.0 %) in the Moorfield and 88 eyes (88.0 %) in the FSM (p=0.001, Fisher’s exact test). In patients with disc area < 2.0 mm2, the FSM (86.7 %) was also more sensitive than the Moorfield (57.8 %) was (p=0.004, Fisher’s exact test), whereas it was 89.1 % in the FSM and 74.4 % in the Moorfield in patients with disc area > 2.0 mm2 (p=0.13, Fisher’s exact test). Conclusions: In Japanese primary open–angle glaucoma eyes, FSM discriminant function value was more sensitive to detect glaucomatous optic disc abnormalities than Moorfield regression classification was.
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