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F. Topouzis, A.L. Coleman, C. Jonescu–Cuypers, F. Yu, A. Harris, L. Mavroudis, E. Anastasopoulos, L. Kagemann, T. Pappas, M.R. Wilson; Comparison of optic disc topographic Heidelberg Retina Tomograph (HRT) parameters between subjects with normal blood pressure (BP) and subjects with systemic hypertension. . Invest. Ophthalmol. Vis. Sci. 2004;45(13):3352.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To compare optic disc HRT measurements between subjects with normal BP and subjects with systemic hypertension. Methods: In 94% of 263 (248) consecutive subjects over 60 yrs of age in Thessaloniki Eye Study, we obtained 3 HRT optic disc measurements. 16 subjects were excluded from analysis, 3 (6 eyes) because of poor quality images and 13 (26 eyes) because of glaucoma diagnosis. 1 eye per subject was randomly selected. 193 (83.2%) of 232 eyes had a mean image created from 3 images while 39 eyes (16.8%) had only one image available for analysis. 2 BP measurements were taken. High BP was defined as systolic BP (SBP) ≥140mmHg and/or diastolic BP (DBP) ≥90mmHg. Subjects were classified based on BP measurements in 3 groups: normal BP (n=60), high BP with or without hypertensive treatment (HT) (n=125) and normal BP secondary to HT (n=47). Subjects were also classified in 2 additional ways: only SBP as criterion (normal SBP n=65, high SBP with or without HT n=113 , normal SBP secondary to HT n=54 ) and only DBP as criterion (normal DBP n=77, high DBP with or without HT n=90 , normal DBP secondary to HT n=65 ). Wilcoxon tests were used to compare the HRT parameters between the 3 groups. Regression models adjusted for disc size, gender, cardiovascular disease, diabetes, IOP and height were used to compare HRT parameters among groups. P<0.01 was considered statistically significant. Results:
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