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M.J. Kossakiewicz, C.N. Ta, L. He, V. Klauss, M.S. Blumenkranz, H. Miño de Kaspar; Antibiotic Resistant Pattern of Conjunctival Streptococci . Invest. Ophthalmol. Vis. Sci. 2004;45(13):4001.
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Antibiotic Resistant Pattern of Conjunctival Streptococci Purpose: To determine the antibiotic susceptibility pattern of streptococcus species isolated from the conjunctiva preoperatively. Methods: Conjunctival cultures were obtained from patients scheduled for intraocular surgery and placed in storage media. Cultures were obtained prior to the application of topical antibiotics or iodine. In this retrospective study, antibiotic susceptibility of isolated streptococci was determined using the Kirby–Bauer disc–diffusion technique. Results: A total of 25 streptococci were identified and isolated. Among these, 19 were non–hemolytic (Enterococcus), 5 α–hemolyitic and 1 ß–hemolytic streptococci. Twenty–three of the 25 (92%) were multiresistant bacteria (defined as resistant to five or more antibiotics tested). None were resistant to gatifloxacin, moxifloxacin, imipenem, and vancomycin (Chart 1.). Compared to gatifloxacin and moxifloxacin, the resistance rate (RR) was significantly higher (P < 0.001) for ciprofloxacin (RR = 40%), ofloxacin (RR = 68%), erythromycin (RR = 72%), neomycin (RR = 88%), gentamycin (RR = 64%) and tobramycin (RR = 80%). Conclusion: Multiresistance streptococci were commonly isolated from the conjunctiva of patients scheduled for intraocular surgery. In this in vitro study Streptococcus species were highly resistant to aminoglycosides, erythromycin, ciprofloxacin and ofloxacin, but none were found to be resistant to gatifloxacin, moxifloxacin, imipenem, or vancomycin. View OriginalDownload SlideView OriginalDownload Slide
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