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J.S. Sarkar, B.Z. Cohen, K.J. Wald, J.C. Paccione; Persistent Elevation of Intraocular Pressure after Intravitreal Injection of Triamcinolone Acetonide . Invest. Ophthalmol. Vis. Sci. 2004;45(13):4086.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To study the occurrence of both transient as well as persistent elevation of intraocular pressure (IOP) following intravitreal injection of triamcinolone acetonide (IVT). Methods: We retrospectively reviewed medical records of 100 patients ( 125 eyes). These patients were treated with 4mg (0.1 ml) of IVT for macular edema secondary to diabetic retinopathy, retinal vascular occlusion and pseudophakia. Follow up period was between 9 – 12 months. Results: Baseline IOP was 15 +/– 3 mm Hg. 15/125 (12 %) of injected eyes had an increase of IOP (range, 22– 38 mm Hg). IOP elevation occured after a period of 4 +/– 2 weeks of injection.Of these, 12 eyes (9.6%) had a transient increase in IOP which returned to baseline within 3–4 months. During this period the IOP was controlled with topical medication. The remaining 3 eyes (2.4%) had a persistently elevated IOP requiring topical medication for more than 6 months. There were no signs of inflammation in the anterior segment of these 3 eyes. None of these 3 patients had a previous or family history of glaucoma. Conclusions: IOP elevation post IVT is transient in the majority of patients however persistent elevation can occur uncommonly.
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