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C. Erb, C. Meiers, C. Kaiser, M. Pfisterer, J. Flammer, H. Kaiser; Color Doppler sonography of the retrobulbar vessels in patients with coronary heart disease . Invest. Ophthalmol. Vis. Sci. 2004;45(13):5255.
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Purpose: It was shown that patients with coronary heart disease (CHD) and otherwise normal ophthalmological status have acquired color vision disturbances and white–noise field campimetry abnormalities. The aim of this study was to clarify whether patients with CHD have disturbances in the retrobulbar perfusion. Methods: Fourty–three male patients with CHD (mean age 56±11 years) and 247 healthy controls (m:f=138:109; mean age 53±16) were included and systolic and diastolic blood pressure determined. The Doppler measurements were performed with a Siemens Quantum 2000 which allows imaging of retrobulbar vessels, measuring their blood flow velocities and calculating their resistivity indices. Results: No differences in systolic and diastolic blood pressure between both groups could be found. However, a significant (p<0.001) reduced blood flow velocity and an increased resistivity index was found in the central retinal artery as well as in the short lateral and medial posterior artery of the patients with CHD. No changes were seen in the ophthalmic artery and the central retinal vein. Conclusions: Patients with CHD have disturbances in the retrobulbar perfusion. This observation in general should be considered in Color Doppler sonography of the retrobulbar arteries to avoid misinterpretations, for example in patients with primary open angle glaucoma.
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