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R.M. Feldman, H.J. Kim, A.Z. Chuang, N.P. Bell; Comparison of Reproducibility and Variability between OCT–3 version 1 and OCT–3 version 2 . Invest. Ophthalmol. Vis. Sci. 2004;45(13):5496.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose:Changes in the optic nerve head (ONH) and retinal nervefiber layers (RNFL) can be quantitatively monitored using animaging device called optical coherence tomography (OCT). Thelatest OCT–3 version 2 contains modifications to the softwaredesigned to improve reproducibility in RNFL measurements. Toevaluate these improvements, data from OCT–3 version 2were compared for reproducibility and variability to those ofOCT–3 version 1.Methods: The cross–sectional images of the RNFL from 16subjects (9 normal, 7 glaucoma) obtained from version 1 werereanalyzed using the new software and intra and inter observervariability calculated. The calculations were compared to thoseof the old software by using Shrout Fleiss coefficients to determineif a significant difference in reproducibility existed betweenthe two versions. Paired t–tests were utilized to establishwhich variables should be considered for use in following glaucomaResults: Overall, OCT–3 version 2 showed higher reproducibilitythan OCT–3 version 1 as indicated by Table 1. For allsubjects, RNFL thickness reproducibility was greater in allmeasured areas except the superior quadrant, where no significantdifference was found Table 1: Comparison of Shrout Fleiss coefficients between version1 and version 2
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