May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Classification of Glaucomatous Visual Field Abnormalities In the Ocular Hypertension Treatment Study (OHTS)
Author Affiliations & Notes
  • J.L. Keltner
    Department of Ophthalmology, University of California, Davis, Sacramento, CA, United States
  • C.A. Johnson
    Discoveries in Sight, Devers Eye Institute, Portland, OR, United States
  • J. Fan
    Department of Mathematics and Statistics, San Diego State University, San Diego, CA, United States
  • K.E. Cello
    Department of Mathematics and Statistics, San Diego State University, San Diego, CA, United States
  • M.O. Gordon
    Department of Ophthalmology and Visual Sciences, Washington University, St. Louis, MO, United States
  • M.A. Kass
    Department of Ophthalmology and Visual Sciences, Washington University, St. Louis, MO, United States
  • Ocular Hypertension Treatment Study Group
    Department of Ophthalmology and Visual Sciences, Washington University, St. Louis, MO, United States
  • Footnotes
    Commercial Relationships  J.L. Keltner, None; C.A. Johnson, None; J. Fan, None; K.E. Cello, None; M.O. Gordon, None; M.A. Kass, None.
  • Footnotes
    Support  NIH grants: EY09307 and EY09341 and Unrestricted Grants from Research to Prevent Blindnes
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 75. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      J.L. Keltner, C.A. Johnson, J. Fan, K.E. Cello, M.O. Gordon, M.A. Kass, Ocular Hypertension Treatment Study Group; Classification of Glaucomatous Visual Field Abnormalities In the Ocular Hypertension Treatment Study (OHTS) . Invest. Ophthalmol. Vis. Sci. 2003;44(13):75.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose: To compare visual field (VF) abnormalities in eyes developing primary open angle glaucoma (POAG) diagnosed by VF abnormality to eyes diagnosed by optic disc deterioration using a classification system developed for OHTS. Methods: The superior and inferior hemifields of all abnormal VFs in OHTS are classified by three certified readers as to type of abnormality using a classification system with 17 categories. This report compares the abnormality classifications of 146 eyes of 125 participants reaching a POAG endpoint; 32% (47 of 146) of these eyes were first diagnosed by abnormal VFs, 60% (87 of 146) by optic disc deterioration, and 8% (12 of 146) by both disc and VFs concurrently. The OHTS protocol requires 3 consecutive abnormal VFS with the same abnormality in the same location for confirmation of VF abnormality; therefore, our analyses included only the first of the 3 replicate abnormal VFs. Results: A total of 47 first abnormal VF endpoints (94 hemifields) were classified from the 47 ‘field first' eyes, and a total of 10 first abnormal VFs (20 hemifields) were classified from the 87 ‘disc first' eyes. Partial arcuate defects were the most common abnormality for both endpoints at 28% of the hemifields (26 of 94) for the ‘field first’ eyes, and 35% of the hemifields (7 of 20) for the ‘disc first’ eyes. Nasal step defects were found in 25% of the hemfields (23 of 94) in ‘field first’ eyes compared to 0% (0 of 20) in the ‘disc first’ eyes. Paracentral defects were found in 12% of the hemifields (11 of 94) in the ‘field first’ eyes compared to 20% (4 of 20) in the ‘disc first’ eyes. Conclusions: A total of 60% of POAG eyes reached an optic disc endpoint first while 40% reached a VF endpoint first or concurrently. Interestingly more nasal step defects were present in ‘field first’ eyes compared to ‘disc first’ eyes. Further investigation will hopefully determine the significance of this finding.

Keywords: visual fields • perimetry • optic disc 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×