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W.C. Stewart, A.G. Konstas, N. Pfeiffer; Patient and Ophthalmologist Attitudes (Views) Concerning Compliance and Dosing in Glaucoma Treatment . Invest. Ophthalmol. Vis. Sci. 2003;44(13):97.
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Purpose: To identify research avenues that, by modifying physician practice, potentially might improve patient compliance. Methods: We interviewed 250 patients and 250 physicians via telephone in France, United Kingdom, Italy, Spain and Germany. The results of the surveys were compiled and evaluated by two independent physicians. Results: This study showed that most physicians believed that reduction of intraocular pressure is useful, although this appeared most important in the United Kingdom (96%), France (94%) and Spain (80%) compared to Italy (72%) and Germany (70%)(P < 0.0001). The majority of physicians believed that noncompliance exists in 0-25% of patients, whereas 34% of patients admitted to noncompliance, most often missing two doses within the previous month. Physicians believed patients would prefer once daily dosing (92%), and that this would help compliance, whereas 60% of patients preferred once daily dosing but only about 20% of patients believed it would assist compliance. Ninety-four percent of physicians believed that noncompliance could lead to visual loss, and while this information concerned most physicians (94%), this was less likely in Germany (52%)(P < 0.0001). Most patients had received information concerning daily dosing of their medicines (79%), and accordingly waited an average of 10 minutes between doses. However, only half had been told to wait at least five minutes between instilling two preparations. Approximately two-thirds of patients knew that missing medicines could cause visual loss. Most patients were unaware of patient oriented glaucoma associations. Conclusions: This study suggests that once daily dosing to increase patient satisfaction and dosing convenience, as well as providing patient education, potentially are clinical techniques that could increase compliance.
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