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S. Melamed, G.J. Ben Simon; Selective Laser Trabeculoplasty (SLT) as Primary Treatment for Open Angle Glaucoma. A Prospective, Non-Randomized Pilot Study . Invest. Ophthalmol. Vis. Sci. 2003;44(13):1183.
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Purpose: To examine the safety and efficacy of Selective Laser Trabeculoplasty (SLT) as primary treatment for patients with Open Angle Glaucoma. Methods: Forty-five eyes of 31 patients with Open Angle Glaucoma (IOP≥23mmHg on two consecutive measurements) underwent selective laser trabeculoplasty as primary treatment. All patients underwent complete ophthalmic evaluation before and at certain intervals after treatment. This included visual acuity, slit-lamp examination, ophthalmoscopy, gonioscopy and visual field analysis. IOP measurements were obtained 1hr, 1day, 1 week, 1,3, 6 and 12 months postoperatively. During the follow-up period patients were treated with topical anti-glaucoma medications as required. Results: Mean IOP (±SD) has decreased by 8.1±3.6 mmHg (31.6%) from 25.6±2.5 mmHg to 17.6±3.2 mmHg (P=0.000). Only two eyes (4.4%) have not responded to SLT, and three eyes (6.7%) required topical medications to control their IOP at the end of the follow-up period. Forty cases (88.9%) had a decrease of 5 or more mmHg. Visual acuity, visual fields and gonioscopy remained unchanged. Complications included conjunctival redness and injection within one day post operatively in 30 eyes (66.7%). One hour after SLT, IOP rise above 5 mmHg was detected in five eyes (11.1%) while IOP rise between 2 and 5 mmHg was measured in three eyes (6.7%). Conclusions: Selective laser trabeculoplasty is effective and safe as a primary treatment for patients with OHT and Open Angle Glaucoma.
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