May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Corneal Thickness and Sensitivity in Keratoconic Subjects
Author Affiliations & Notes
  • S. Thota
    Optometry, University of Houston, TERTC, Houston, TX, United States
  • W.L. Miller
    Optometry, University of Houston, TERTC, Houston, TX, United States
  • A. Minavi
    Optometry, University of Houston, TERTC, Houston, TX, United States
  • J. Jackson
    Optometry, University of Houston, TERTC, Houston, TX, United States
  • N. Leach
    Optometry, University of Houston, TERTC, Houston, TX, United States
  • J. Bergmanson
    Optometry, University of Houston, TERTC, Houston, TX, United States
  • Footnotes
    Commercial Relationships  S. Thota, None; W.L. Miller, None; A. Minavi, None; J. Jackson, None; N. Leach, None; J. Bergmanson, None.
  • Footnotes
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Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1317. doi:
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    • Get Citation

      S. Thota, W.L. Miller, A. Minavi, J. Jackson, N. Leach, J. Bergmanson; Corneal Thickness and Sensitivity in Keratoconic Subjects . Invest. Ophthalmol. Vis. Sci. 2003;44(13):1317.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: The relationship of corneal sensitivity and thickness measurements of established gas permeable keratoconic subjects was evaluated in this study. Methods: Corneal measurements were taken on both eyes of nine keratoconic subjects (Age range 21-38; average 30). Corneal sensitivity was determined immediately after lens removal by a slit-lamp mounted Cochet-Bonnet aesthesiometer. Three consecutive measurements from the central and inferior mid-peripheral cornea were averaged. Using an OrbScan topographer, pachymetry readings were collected from six different locations on the cornea. Results: Mean central sensitivity was 3.98mm and 4.02mm; mean peripheral sensitivity was 4.83mm and 4.93mm right and left eyes respectively. However, there was no statistical difference between central and peripheral corneal sensitivities in either eye (paired t-test, two-tailed). Sensitivity of the right and left central corneas showed a mild correlation with the cone thickness of the right and left eyes respectively. Conclusions: The peripheral cornea showed a slightly greater corneal sensitivity compared to the central cornea. However, the central corneal sensitivity data showed a greater variance when compared to the peripheral cornea. The majority of subjects exhibited an inferior cone, which may help to explain the increased sensitivity in the peripheral cornea. Data suggests a lack of correlation between peripheral corneal sensitivity and cone thickness, but supports a correlation between central corneal sensitivity and cone thickness of keratoconic patients.

Keywords: keratoconus • cornea: clinical science • cornea: clinical science 
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