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K.H. Hammersmith, E.J. Cohen, C.J. Rapuano, D.M. Najjar, P.R. Laibson; Blepharokeratoconjunctivis in Children . Invest. Ophthalmol. Vis. Sci. 2003;44(13):1408.
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Purpose: Chronic blepharokeratoconjunctivitis is an important and underdiagnosed ocular disease in children, characterized by lid inflammation, conjunctival hyperemia and peripheral keratitis. The purpose of this study is to evaluate the incidence, symptoms, signs and treatment of blepharokeratoconjunctivitis in a pediatric population in a tertiary cornea practice. Design: Retrospective case series. Methods: To determine the incidence of cases, we reviewed the medical records of new pediatric (children less than or equal to 12 years) patients from 1999 to 2001, noting the reason for referral and subsequent diagnosis. We further noted the history, clinical characteristics, and treatment of the patients with blepharokeratoconjunctivitis. Results: Blepharokeratoconjunctivitis was diagnosed in 16 of the 88 (18.1%) new patients, with an equal number of boys and girls affected (n=8). The average age at presentation was 6 .3 years (range: 2-11 years). The most common presenting complaints were redness (37.5%) and recurrent chalazia (31.3 %). Bilateral disease was noted in all patients (100%). Topical steroids were used in the treatment in 6 cases (37.5%) and oral erythromycin was employed in 12 patients (75%). Therapy was well-tolerated and effective in most patients. Conclusion: Blepharokeratoconjunctivis is a common disease in children, which often requires systemic erythromycin treatment.
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