May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Risk of Traumatic Endophthalmitis With and Without Intravenous Antibiotic Prophylaxis
Author Affiliations & Notes
  • J. Zink
    Opthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, United States
  • A. Ketafian
    Opthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, United States
  • T. Lin
    Opthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, United States
  • D. Musch
    Opthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, United States
  • Q. Farjo
    Opthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, United States
  • S. Mian
    Opthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, United States
  • Footnotes
    Commercial Relationships  J. Zink, None; A. Ketafian, None; T. Lin, None; D. Musch, None; Q. Farjo, None; S. Mian, None.
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1450. doi:
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      J. Zink, A. Ketafian, T. Lin, D. Musch, Q. Farjo, S. Mian; Risk of Traumatic Endophthalmitis With and Without Intravenous Antibiotic Prophylaxis . Invest. Ophthalmol. Vis. Sci. 2003;44(13):1450.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: The goal of this study is to determine whether prophylactic intravenous antibiotics reduce the incidence of endophthalmitis following traumatic open globe injury. Methods: Retrospective chart review of 88 patients presenting with traumatic open globe injury. The mean age was 35.55 +/- 22.3 years (2 – 92) with 80.7% male and 19.3% female. Statistical analysis was performed using the chi-square test. Results: Visual acuity at presentation was > 20/400 in 18.9%, CF to HM in 29.7% and LP/NLP in 51.4%. Visual acuity at last follow-up was > 20/40 in 33.3% and LP/NLP in 35.8% with 25.9% requiring enucleation. Visual acuity at last follow-up was NLP in 16.1% in anterior globe injuries, NLP in 61.9% of posterior globe injuries, and > 20/40 in 69.2% of open globes with injury site < 5mm. The overall incidence of endophthalmitis was 3/88 (3.4%). Endophthalmitis incidence for patients receiving no intravenous antibiotics 2/45 (4.4%) was not statistically different from those receiving perioperative 1/41 (2.4%; Yates' chi-square, p=0.77) or postoperative antibiotics 1/14 (7.1%; Yates' chi-square, p=0.93). Conclusions: Intravenous antibiotics may not reduce the incidence of traumatic endophthalmitis. Postoperative inpatient care for traumatic open globe injuries may not be necessary.

Keywords: endophthalmitis • antibiotics/antifungals/antiparasitics 
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