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M.W. Wilson, C.B. Pratt, B.G. Haik, C. Rodriguez-Galindo; Anterior Versus Posterior Tumors in Patients with Retinoblastoma Treated with Primary Systemic Chemotherapy . Invest. Ophthalmol. Vis. Sci. 2003;44(13):1576.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To report differences in control rates of anterior versus posterior tumors in retinoblastoma patients treated with primary systemic chemotherapy. Methods:Records of 37 consecutive patients (35 multi-/ 2 unifocal) with intraocular retinoblastoma treated with primary systemic chemotherapy were reviewed to determine which tumors were controlled with chemotherapy alone. Results:150 tumors in 66 eyes were identified; 83 were posterior and 57 anterior to the equator. Twenty-five posterior (30%) and 4 anterior tumors (7%) were treated with chemotherapy alone. Median follow-up was 27 months. Conclusions: Chemotherapy is successful in treating selected posterior tumors in patients with retinoblastoma. Careful observation, with timely consolidation, may permit preservation of visually important structures.
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