May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Anterior Versus Posterior Tumors in Patients with Retinoblastoma Treated with Primary Systemic Chemotherapy
Author Affiliations & Notes
  • M.W. Wilson
    Ophthalmology, University of Tennessee, Memphis, TN, United States
  • C.B. Pratt
    Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, TN, United States
  • B.G. Haik
    Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, TN, United States
  • C. Rodriguez-Galindo
    Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, TN, United States
  • Footnotes
    Commercial Relationships  M.W. Wilson, None; C.B. Pratt, None; B.G. Haik, None; C. Rodriguez-Galindo, None.
  • Footnotes
    Support  NIH Grant CA23099, ALSAC, Research to Prevent Blindness, Inc, New York, New York
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1576. doi:
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    • Get Citation

      M.W. Wilson, C.B. Pratt, B.G. Haik, C. Rodriguez-Galindo; Anterior Versus Posterior Tumors in Patients with Retinoblastoma Treated with Primary Systemic Chemotherapy . Invest. Ophthalmol. Vis. Sci. 2003;44(13):1576.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To report differences in control rates of anterior versus posterior tumors in retinoblastoma patients treated with primary systemic chemotherapy. Methods:Records of 37 consecutive patients (35 multi-/ 2 unifocal) with intraocular retinoblastoma treated with primary systemic chemotherapy were reviewed to determine which tumors were controlled with chemotherapy alone. Results:150 tumors in 66 eyes were identified; 83 were posterior and 57 anterior to the equator. Twenty-five posterior (30%) and 4 anterior tumors (7%) were treated with chemotherapy alone. Median follow-up was 27 months. Conclusions: Chemotherapy is successful in treating selected posterior tumors in patients with retinoblastoma. Careful observation, with timely consolidation, may permit preservation of visually important structures.

Keywords: retinoblastoma • oncology • tumors 
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