May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Optical Coherence Tomography (OCT) for the Follow-Up of Subfoveal Choroidal Neovessels in Age Related Macular Degeneration: Features Associated With Poor or Fair Visual Prognosis
Author Affiliations & Notes
  • I.A. Meunier
    Fondation A de Rothschild, 75019 Paris, France
  • D. Iossifov
    Fondation A de Rothschild, 75019 Paris, France
  • A. Merdassi
    Fondation A de Rothschild, 75019 Paris, France
  • C. Favard
    Fondation A de Rothschild, 75019 Paris, France
  • G. Caputo
    Fondation A de Rothschild, 75019 Paris, France
  • P. De Laage de Meux
    Fondation A de Rothschild, 75019 Paris, France
  • Footnotes
    Commercial Relationships  I.A. Meunier, None; D. Iossifov, None; A. Merdassi, None; C. Favard, None; G. Caputo, None; P. De Laage de Meux, None.
  • Footnotes
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Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1754. doi:
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      I.A. Meunier, D. Iossifov, A. Merdassi, C. Favard, G. Caputo, P. De Laage de Meux; Optical Coherence Tomography (OCT) for the Follow-Up of Subfoveal Choroidal Neovessels in Age Related Macular Degeneration: Features Associated With Poor or Fair Visual Prognosis . Invest. Ophthalmol. Vis. Sci. 2003;44(13):1754.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To analyze and to identify the OCT features associated with worse final visual acuity in patients with subfoveal neovascularization treated with photodynamic therapy (PDT). Methods: The medical records of 26 consecutive patients with classic subfoveal neovascularization treated with PDT (at least two sessions) and with OCT-imaging follow up were retrospectively reviewed. Among these patients, two groups were separated accorded to the final visual acuity level, i.e. patients with stabilized or improved visual acuity (n=10) and patients with decreased visual acuity (n=16). In these two groups, the data of the last OCT records were compared. Results: Macular edema was disclosed in 56% of patients in the worsened group versus 20% in the stabilized group. Mean retinal thickness was 390µm in the worsened group versus 240µm in the stabilized group. A fovea elevation was observed in 69% of the worsened group versus 30% in the stabilized group. Localized serous detachment was noted in 38% of the worsened group versus 10% in the stabilized group. Conclusion: These results based on OCT imaging suggest that macular edema, retinal thickening and fovea elevation are correlated with worse visual acuity and could indicate a lower response of the choroidal neovessels to PDT.

Keywords: age-related macular degeneration • neovascularization • imaging/image analysis: clinical 
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