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G. Soubrane, W. Roquet, W. Haddad, G. Coscas, E. Souied; Evaluation of a New Approach for Analysis of Fluorescein Angiography: The Simedge Eyetoolkit Software® . Invest. Ophthalmol. Vis. Sci. 2003;44(13):1820.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To evaluate and optimise a new software in order to improve and simplify the analysis of fluorescein angiography (FA). Methods: Sequences of fluorescein angiograms of patients harbouring various patterns of exudative AMD before of after treatment were selected in order to visualise active leakage of dye. On the other hand, images of follow up (7 to 15 years) from macular dystrophies were retrospectively selected in order to precise the natural history of the disease. Images were issued from printed photographs or any digital instrument and submitted to the Eyetoolkit software. Results: Eyetoolkit softare performed an automatic, efficient and rapid overlay (0.5 to 3 seconds) from the selected frames. In exudative AMD patients (50 eyes), the overlay applied in a movie mode obviously demonstrated the progressive enlargement of the hyperfluorescence , materializing the leakage of fluorescein . In inherited macular dystrophy cases, a movie overlaying images from successive angiograms permitted an obvious display of the progression of the disease. The resulting movies could be seen either with the Eyetoolkit software or be exported to video format. Conclusions: Eyetoolkit is a new automatic and efficient tool for a rapid overlay of images, obtaining a FA movie- from any images. It leads to easy visualisation of leakage from choroidal newvessels, particularly helpful for the decision of re-treatment. Easy visibility of the kinetics of the dye in angiography or during the natural history in macular dystrophies, in a movie mode, also represents an useful approach for teaching.
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