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L.A. Paunescu, L.L. Price, P.C. Stark, S. Beaton, H. Ishikawa, G. Wollstein, J.G. Fujimoto, J.S. Schuman; OCT 3 Measurement Reproducibility of Nerve Fiber Layer Thickness, Macula Thickness Map and Optic Nerve Head Analysis on Normal Subjects . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2173.
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Purpose: To evaluate the reproducibility of the nerve fiberlayer (NFL) thickness, macula thickness map and optic nervehead (ONH) parameters generated by the OCT 3 (Optical CoherenceTomography 3, software version A1, Carl Zeiss Meditec Inc.,Dublin, CA).Methods: Normal subjects were imaged 6 times (3before and 3 after dilation) per day on each of 3 separate days.The scan type order (NFL, macula, and ONH) was randomized foreach session and subject. We used variance components analysiswith random effects mixed models to determine intraclass correlationcoefficients (ICCs), inter-visit, intra-visit and standard deviations(SDs) as measures of reproducibility and to study the effectof dilation on retinal, NFL and ONH parameters.Results: 10eyes of 10 normal subjects were enrolled (mean age 30.1 ±7.6 years). SDs of 3 different scan types are summarized inTable 1 and ICCs in Table 2. View OriginalDownload SlideView OriginalDownload Slide View OriginalDownload SlideView OriginalDownload Slide
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