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R.S. Cady, R.C. Mudumbai, P.P. Chen; Visual Field Stability in Eyes With Open Angle Glaucoma That Have Previous Visual Field Progression . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2212.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To evaluate visual field stability in eyes diagnosed with open angle glaucoma which have previously shown visual field progression by AGIS scoring and/or modified Anderson criteria. Methods: Fifty-four eyes of fifty-four consecutive patients with primary open-angle glaucoma, pseudoexfoliative glaucoma, normal tension glaucoma, or pigmentary glaucoma, seen over a 7 month period, who demonstrated previous visual field progression, were evaluated for further progression. Visual field progression was defined by the use of modified Anderson criteria and required a worsening of 3 adjacent points on 2 consecutive visual field tests. Patients were followed with Humphrey perimetry for a minimum of 2 years. Mean patient age was 60.4 years (SD 11.5 years) and mean follow up time was 100 months (SD 44 months). Potential risk factors were evaluated using standard statistical analysis. Results: Thirty-two of fifty-four eyes (59.3%) showed at least one further step of progression. Ten of those thirty-two showed at least two further steps of progression. Age, sex, race, family history, refraction, months of follow up, years of disease, mean or maximum intraocular pressure, initial cup to disc ratio, visual field mean deviation or pattern standard deviation, presence or absence of a disc hemorrhage, cardiovascular disease, hypertension, and diabetes mellitus were not significant risk factors for a second or third step of progression. Conclusions: In this study population, 59.3% of eyes with prior visual field progression underwent a second step of progression. Additionally, 18.5% of eyes demonstrated a third step of progression. An important risk factor for future progression is prior progression.
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