May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Temporal Changes of Tear Film Break-Up Observed by a Real Time Hartmann-Shack Wavefront Aberrometer
Author Affiliations & Notes
  • T. Mihashi
    Technical Research Institute, Topcon Corporation, Itabashi-Ku, Japan
  • Y. Hirohara
    Technical Research Institute, Topcon Corporation, Itabashi-Ku, Japan
  • T. Kuroda
    Medical School, Osaka University, Suita, Japan
  • N. Maeda
    Medical School, Osaka University, Suita, Japan
  • T. Fujikado
    Medical School, Osaka University, Suita, Japan
  • T. Oshika
    Department of Ophthalmology, University of Tsukuba, Tsukuba, Japan
  • Footnotes
    Commercial Relationships  T. Mihashi, Tocon Corporation E; Y. Hirohara, Topcon Corporation E; T. Kuroda, None; N. Maeda, Alcon C; T. Fujikado, None; T. Oshika, None.
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2541. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      T. Mihashi, Y. Hirohara, T. Kuroda, N. Maeda, T. Fujikado, T. Oshika; Temporal Changes of Tear Film Break-Up Observed by a Real Time Hartmann-Shack Wavefront Aberrometer . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2541.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose: Wavefront aberrations were induced by tear film break-up(Koh S, et al, Am J Ophthalmol, 134, (2002) 115-7). To develop a novel method for measuring a onset time of the break-up and its rates, higher-order wavefront aberrations were measured continuously after blinking using a Hartmann-Shack wavefront aberrometer. Methods: Wavefront aberrations up to 6th order for 4 mm pupil were measured for four eyes of four normal subjects using a Hartmann-Shack wavefront aberrometer specially built for this purpose. The aberrometory was performed on each case once every second up to forty seconds under topical anesthesia. We plotted RMSs of higher-order wavefront aberration(HWA) versus temporal duration after blinking for each case. The sequence of the points in each plot were divided into a steady state, in which the slope of the regression of this group of points was relatively flat, and a break-up state, in which the slope was relatively steep. We set that the onset of the break-up was the border of the two states and the temporal rate was the slope of the break-up state. Results: Four sequences we measured were easily divided into two states respectively, including the sequence shown in Fig. 1. The onset times for four cases were 11.3, 15.8, 8.0 and 8.0 s. The rates of the break-up were 8.1, 3.7, 7.4 and 0.7 nm / s.  

Keywords: cornea: tears/tear film/dry eye • optical properties • cornea: clinical science 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×