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C.W. Winkler von Mohrenfels, C.P. Lohmann, A. Kempe, W. Herrmann, B. Gabler, V.P. Gabel; Different Ablations Frequencies for Excimer Laser Ablation (50, 200 and 500 Hz) - Influence on the Corneal Cell Damage . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2626.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To make the excimer ablation more convenient for the patient, the excimer lasers are getting faster and faster (up to 500 Hz). Aim of this study was to investigate the changes in corneal cell damage with different ablation frequencies (50, 200 and 500 Hz). Methods: PRK and LASIK were performed on porcine cadaver eyes using a Wavelight Concept 500 excimer laser. At various repetition rates (50, 200 and 500 Hz) corrections between +6 and -9 D have been performed. Corneal cell damage was investigated pre- and postoperatively using endothelial cell microscopy. Postoperatively, the cornea was removed from the eye and the cell damage was investigated by light microscopy (HE-, Picrosirius red staining) and electron microscopy. Results: We could not find any significant changes in the number and in the appearance of the endothelial cells in relation to ablation depth and/or repetition rate. Also there were no differences in the cell damage in light and electron microscopy. Conclusions: The Wavelight Concept 500 is a safe excimer laser with a frequency of 500 Hz. This laser system has the advantage that the treatment time is as fast as with broad beam lasers.
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