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M.R. Chalita, S. Waheed, M. Xu, R.R. Krueger; Wavefront Analysis in Post-LASIK Eyes and its Correlation with Visual Symptoms, Refraction and Topography . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2651.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To evaluate the information assessed with the LADARWave wavefront measurement device and correlate it with visual symptoms, refraction and corneal topography in previously LASIK treated eyes. Methods: One hundred and five eyes (58 patients) of individuals that underwent LASIK surgery were evaluated. Wavefront measurements were assessed using the LADARWave wavefront measurement device. Complete ophthalmologic exam, corneal topography and wavefront measurements were performed. Correlations between the exams and symptoms were made. Manifest, cycloplegic refraction and topographical data were compared to wavefront refraction and higher order aberrations. Visual symptoms were correlated to higher order aberrations in three different pupil sizes (5mm, 7mm and scotopic pupil size). Pearson’s correlation coefficient and generalized estimating equations (GEE) were used for statistical analysis. Results: In post-LASIK eyes, wavefront refraction components were poorly correlated to manifest and cycloplegic components. The comparison between manifest, cycloplegic and wavefront refraction with total amount of higher order aberrations showed no strong correlation. The comparison between topography and manifest, cycloplegic and wavefront refraction did not show strong correlation. Visual symptoms analysis showed: correlation of double vision with total coma (p=0.008, p=0.014) and with horizontal coma (p=o.014, p=0.024) for the 5mm and 7mm pupil size, respectively; correlation between starburst and total coma for the 7mm pupil size (p=0.038); and correlation of double vision with horizontal coma (p=0.033), glare with spherical aberrations (p=0.010) and with total aberrations (p=0.041), and starburst with spherical aberrations (p=0.014) for the scotopic pupil size. Scotopic pupil size had positive association with starburst (p=0.001) and negative association with double vision (p=0.011). Conclusions:The LADARWave wavefront measurement device is a valuable diagnostic tool in measuring refractive error with ocular aberrations in post-LASIK eyes. A strong correlation between visual symptoms and ocular aberrations, such as monocular diplopia with coma and starburst and glare with spherical aberration, suggest this device is valuable in diagnosing symptomatic LASIK induced aberrations. Horizontal coma was correlated with double vision, while vertical coma was not.
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