May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Relationship Between Total Aberrations (RMS) and Pupil Size in Ametropic Eyes With the LADARWave System
Author Affiliations & Notes
  • E. Maguen
    Ophthalmic Clinical Trials Ctr, Cedars-Sinai Medical Center, Los Angeles, CA, United States
  • J. Schlanger
    Ophthalmic Clinical Trials Ctr, Cedars-Sinai Medical Center, Los Angeles, CA, United States
  • J. Wong
    Ophthalmic Clinical Trials Ctr, Cedars-Sinai Medical Center, Los Angeles, CA, United States
  • J.J. Salz
    Ophthalmic Clinical Trials Ctr, Cedars-Sinai Medical Center, Los Angeles, CA, United States
  • Footnotes
    Commercial Relationships  E. Maguen, None; J. Schlanger, None; J. Wong, None; J.J. Salz, Alcon C, R.
  • Footnotes
    Support  support: Discovery Fund for Eye Research
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2686. doi:
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      E. Maguen, J. Schlanger, J. Wong, J.J. Salz; Relationship Between Total Aberrations (RMS) and Pupil Size in Ametropic Eyes With the LADARWave System . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2686.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To evaluate the relationship between pupil size and total aberrations as represented by the root mean square value (RMS) in ametropic, otherwise normal eyes. Methods: 22 eyes (11 patients) had diagnostic wavefront measurements with both undilated and dilated pupils. Total aberrations, spherical aberration, and coma were recorded using RMS values. Software integrated within the LADARWave system allowed simulation of all of the above aberrations for increments of 0.5mm of pupil dilation. Results: A linear relationship was found in all eyes between pupil diameter and total aberrations as expressed in RMS, with a high coefficient of determination (R2). The mean R2 ±SD was 0.9515±0.0334 (range: 0.886-0.9835). The slope was variable. Conclusions: This data shows the existence of a direct relationship between pupil diameter and the total amount of higher order aberrations as expressed by RMS with the LADARWave system . The variable slope needs to be further investigated as it may correlate with symptoms related to the presence of higher order aberrations both in the normal state and postoperatively.

Keywords: refractive surgery • laser • pupil 
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