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H. Zou, X. Zhang, X. Xu; Prevalence and Risk Factors of Age-Related Macular Degeneration in the Chinese People: The CJD Study . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3081.
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Background: A recent prevalence study showed that the prevalence of age-related macular degeneration (AMD) in a rural old Chinese population was 8.4%. But no similar study has done in urban population during the past ten years. Purpose: To assess the prevalence and potential risk factors for AMD in the urban old people from Caojiadu block, Shanghai, P.R.China. Methods: After sample estimation, 1054 Chinese race urban people older or equal to 60 were chosen as sample from the total population (12269). Clinical evaluations consisted of a medical history review, ocular examination and fundus photographs. Presence and classification of AMD were determined via photographs. Results: 156(14.8%) persons were identified as AMD patients. Comparing to the no-AMD persons, the prevalence of AMD was strongly age related (p=0.01). Overall, AMD was present in 12.2% of the population aged 60 to 70 years, rising to 18.3% of the population older than 71 years. Alcohol consumption was another risk factor consistently associated with AMD (p=0.05). There were no significant gender differences in the prevalence of any form of AMD. Apart from that, tobacco smoking, hypertension, diabetes and cardiovascular disease were all excluded from the group of risk factors associated with AMD. Conclusions: The prevalence of AMD in recent urban old Chinese people is higher than that of rural people. In this study, age and alcohol consumption were the risk factors related to AMD.
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