Purchase this article with an account.
M. Miyazaki, H. Nakamura, M. Kubo, Y. Kiyohara, T. Ishibashi; Prevalence and Risk Factors for Retinopathy with Diabetes and Impaired Glucose Tolerance in a Japanese Population: The Hisayama Study . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3095.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
Purpose: To determine the prevalence and risk factors for diabetic retinopathy in people with non-insulin-dependent diabetes mellitus and impaired glucose tolerance in a sample Japanese population. Methods: Representative population-based samples of people aged 40-79 years old selected from a Japanese community, Hisayama, Japan were studied. In 1998, a cross-sectional community survey was conducted among a total of 1950 residents of Hisayama. Each participant underwent a comprehensive examination that included a 75-g oral glucose-tolerance test and ophthalmic examinations. A 75-g oral glucose-tolerance test was used to classify participants into normal, impaired glucose tolerance and non-insulin-dependent diabetes mellitus groups. The presence of diabetic retinopathy was judged from grading based on fundus examination using indirect ophthalmoscopy, slit lamp, and color fundus photographs. Multivariate logistic regression analyses were performed on the cross-sectional data to determine the risk factors for diabetic retinopathy. Results: There were 37 subjects (2.3%) who had any diabetic retinopathy. The prevalence of retinopathy was 18.6% in subjects with non-insulin-dependent diabetes mellitus, while it was 1.1% in those with impaired glucose tolerance. Multivariate analysis showed that duration of diabetes and 2-hour postloading glucose level were significant independent risk factors for diabetic retinopathy in Japanese subjects. Conclusions: This study suggests that the prevalence rate of retinopathy is similar to those in population-based studied performed in white populations, but lower than those in black populations and Hispanic, and that duration of diabetes and 2-hour postloading glucose level were significant independent risk factors for diabetic retinopathy.
This PDF is available to Subscribers Only