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M. Abrahamsson, H. Kalm; Central Retinal Vein Occlusion (CRVO) - Study Patients for Early Intervention Therapy . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3108.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To determine the frequency of possible study patients for early intervention therapy of CRVO within an epidemiological well defined population and to estimate the possible gain in terms of saved sight and prevented need of thermal therapy. Methods: Retrospective data from files on patients with a debut of CRVO Jan. 1999 unto Jan. 2003, Västra Götaland County, Sweden, a source population of 1.5 million. Files were identified by DRG, a diagnosis report system. Results: A total of 400 patients were identified (November 2002). Almost half of the patients had a CRVO duration of two weeks or less and as many more than one month. Visual acuity (VA) 0.4 or better was recorded in 20% and less than 0.1 in 40% of the patients. Neovascularization developed in half of all patients followed for one year. VA in those patients was as a rule 0.1 or less at that specific end-point and further deterioration occurred. Visual survivors (improved or stable VA) were found among patient younger than 55 years having a 50% chance of improvement whereas this was rare, 7% in patient older than 60 years, however increasing to 20% if VA 0.5 or better at first visit. Treated glaucoma was a common finding. Conclusions: CRVO in elderly patients cause irreversible, substantial visual loss in general. Patients older than 55 years, with disease duration of two weeks or less and VA at any level, are of potential interest when planning early CRVO intervention studies in our population.
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