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J. Berrod, O. Naoun, P. Alle, V. Dorr, A. Benoit; Assessment of Retinal Nerve Fiber Layer Thickness by Use of Optical Coherence Tomography and Retinal Dichroïsm Measurement: Preliminary Study . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3397.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To assess the correlation between the results of retinal dichroïsm and optical coherence tomography to measure the thickness of the retinal nerve fiber layer. Methods: 12 patients were evaluated : 6 normal, 6 glaucomatous. Complete ophthalmologic examination, disk photography, automated achromatic perimetry, optical coherence tomography, and retinal dichroïsm analysis were performed. The linear dichrograph, developed by the authors, uses unpolarized light and analyse scattered back light partially polarized. The resulting measurement is based on the variation of light absorption with the direction of polarization plane. Results: A good correlation between optical coherence tomography, dichroïsm analyzer, and visual field for normal and glaucomatous subjects was obtained. Optical coherence tomography and dichroïsm analyzer were capable of differentiating between glaucomatous and normal subjects. Conclusion: Dichroïsm analyzer and optical coherence tomography show good potential for exploring retinal fiber layer thickness. In order to confirm the correlation between the two methods, a larger study of normal, ocular hypertensive, and glaucomatous is currently underway.
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