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J. Nordmann, N. Hamelin, G. Berdeaux; Vision Related Quality of Life of French Patients is Affected by Topical Glaucoma Treatment Side Effects . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3419.
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Purpose To evaluate the consequences of local anti-glaucoma drug side effects on the vision-related quality of life (QoL). Methods A mail survey was sent to 20,000 homes of a panel representative of the French population asking whether one member of the family was suffering from ocular hypertension (OH) or glaucoma. A computer-assisted telephone interviewing system was used to confirm self-reported glaucoma, to describe the disease and its treatment, and medical item consumption. Vision-related QoL was assessed with the NEI-VFQ-25 and local tolerance with the COMTOL. Results 13,352 homes (66.7%) answered the mail. 581 people declared they were suffering from glaucoma or OH. Prevalence was 1.8%, increasing with age. 204 patients were selected at random Their NEI-VFQ-25 global score showed an overall good QoL. Two domain scores showed some deterioration: general health and driving. 62.4% of the patients cited at least one local side effect. 25.4% had burning, 20.8% blurred vision and 20.2% tearing. Vision related QoL was affected by local side effects leading to poor perceived treatment satisfaction that impacted compliance. Dissatisfied patients visited their ophthalmologist more frequently. Conclusion : Based on a representative French sample, vision related QoL is affected by topical drug side effects that also impact patient satisfaction, compliance and cost.
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