May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Topic Cyclosporine "A" in the Management of Allergic Conjunctivitis
Author Affiliations & Notes
  • P. Velasco
    Cornea, Hospital Nstra Sra De La Luz, Mexico City, Mexico
  • O. Baca
    Cornea, Hospital Nstra Sra De La Luz, Mexico City, Mexico
  • R. Velasco
    Cornea, Hospital Nstra Sra De La Luz, Mexico City, Mexico
  • D. Viggiano
    Cornea, Hospital Nstra Sra De La Luz, Mexico City, Mexico
  • C. Cardona
    Cornea, Hospital Nstra Sra De La Luz, Mexico City, Mexico
  • Footnotes
    Commercial Relationships  P. Velasco, None; O. Baca, None; R. Velasco, None; D. Viggiano, None; C. Cardona, None.
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 3798. doi:
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    • Get Citation

      P. Velasco, O. Baca, R. Velasco, D. Viggiano, C. Cardona; Topic Cyclosporine "A" in the Management of Allergic Conjunctivitis . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3798.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To assess the efficiency of topic Cyclosporine "A" with two different concentrations in patients with mild to severe allergic conjunctivitis. Methods: This is a prospective, comparative and longitudinal study held at the Cornea Department. We stratified into 3 different groups: 1) Seasonal or Pereneal Allergic Conjunctivitis, 2) Vernal Keratoconjunctivitis, and 3) Atopic Keratoconjunctivitis, treated with cyclosporine "A" with a random concentration of 1 mg/ml (0.1%) and 2 mg/ml (0.2%), with a weekly photographic follow up, for at least a month. We assess the following symptoms: ocular grittines, ocular pain, watering, photophobia, itching, and foreign body sensation. Graduating them from absent, mild, moderate, or severe. We assess the following signs too: lid swelling, conjunctival congestion, papillary reaction, Trantas reaction, and superficial punctate keratitis (SPK). Those signs were compared with standard pictures and graduate from absent to severe. Results: We studied 18 patients: 5 in group One, 9 in group Two, and 4 in group Three. Three patients (16.7%) were intolerant to the treatment. The rest of them had satisfactory evolution with a 50% of symptomatic relief within the first week of treatment. Patients on group One had the best response to treatment. We found no difference between the 0.1% and 0.2% cyclosporine. Conclusions: The management of allergic conjunctivitis with topic cyclosporine "A" has a satisfactory evolution in 83.3% of the patients, with a 50% of symptomatic relief with the first week of treatment.

Keywords: cyclosporine • conjunctivitis 
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