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M.P. Jones, O. Oz, M.A. Herion, L. Akduman; Factors Predicting a Successful Outcome of Vitrectomy for Diabetic Macular Edema . Invest. Ophthalmol. Vis. Sci. 2003;44(13):4024.
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Purpose: To report factors predicting a successful outcome in the treatment of persistent diabetic macular edema with vitrectomy. Methods: 20 eyes of 17 patients with diabetic macular edema and taut hyaloid that did not respond to laser photocoagulation underwent vitrectomy, peeling of the posterior hyaloid and interior limiting membrane if prominent. Predictive value of pre-operative factors such as CME, history of PRP, lens status, and insulin dependence were studied. Outcome measures were improvement of vision and resolution of macular edema. Results: The average pre-operative visual acuity was 20/372, with a median of 20/90. The average post-op visual acuity was 20/167 with a median of 20/85. Ten of the eyes (50%) showed post-op visual acuity improvement of ≥ 2 lines; 5 eyes (25%) showed no change and 5 eyes (25%) had worse visual acuity by ≥ 2 lines. None of the pre-operative variables studied, including presence of pre-op CME, insulin use, pre-op PRP, or phakia had any statistically significant effect on the outcomes of visual acuity or post-op macular edema. Conclusions: Among patients with resistant diabetic macular edema, factors such as the presence of pre-operative CME, the use of insulin, pre-operative PRP, or lens status did not have any statistically significant effects on post-operative visual acuity or macular edema.
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