December 2002
Volume 43, Issue 13
Free
ARVO Annual Meeting Abstract  |   December 2002
Tear Function Tests and Conjunctival Impression Cytology Before and After Hormone Replacement Therapy in Postmenopausal Women
Author Affiliations & Notes
  • A Pelit
    Ophthalmology Baskent University Medical Faculty Adana Turkey
  • T Bagis
    Obstetrics and Gynecology
    Baskent University Adana Turkey
  • F Kayaselcuk
    Pathology
    Baskent University Adana Turkey
  • D Dursun
    Ophthalmology Baskent University Ankara Turkey
  • Y Akova
    Ophthalmology Baskent University Ankara Turkey
  • P Aydin
    Ophthalmology Baskent University Ankara Turkey
  • Footnotes
    Commercial Relationships   A. Pelit, None; T. Bagis, None; F. Kayaselcuk, None; D. Dursun, None; Y. Akova, None; P. Aydin, None.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 104. doi:
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      A Pelit, T Bagis, F Kayaselcuk, D Dursun, Y Akova, P Aydin; Tear Function Tests and Conjunctival Impression Cytology Before and After Hormone Replacement Therapy in Postmenopausal Women . Invest. Ophthalmol. Vis. Sci. 2002;43(13):104.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To investigate the effect of hormone replacement therapy (HRT) on postmenopausal tear function tests and conjunctival epithelium. Methods: We performed Schirmer I test, tear film break-up time (BUT) and impression cytology tests on 34 eyes of 17 cases, having menopause at least for 2 years and taking no HRT. Same processes were repeated after 3 months following HRT. Results: : Average age of the cases was 53.82±3.6 years and average menopause time was 35.29±11.59 months. There was no significant difference before and after HRT considering Schirmer I test (p≷0.05), however BUT (p<0.05) and impression cytology (p<0.05) results were significantly different after therapy. Conclusion: We concluded that HRT could alleviate the postmenopausal dry eye symptoms by increasing goblet cell density.

Keywords: 376 cornea: tears/tear film/dry eye • 365 conjunctiva • 381 cytology 
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