December 2002
Volume 43, Issue 13
Free
ARVO Annual Meeting Abstract  |   December 2002
Optical Coherence Tomography (OCT) for the Detection of Laser in Situ Keratomileusis (LASIK) in Donor Corneas
Author Affiliations & Notes
  • AS Neubauer
    Dept of Ophthalmology Ludwig-Maximilians University Muenchen Germany
  • SG Priglinger
    Dept of Ophthalmology Ludwig-Maximilians University Muenchen Germany
  • C-A May
    Dept of Anatomy Friedrich Alexander University Erlangen Germany
  • CS Alge
    Dept of Ophthalmology Ludwig-Maximilians University Muenchen Germany
  • K Ludwig
    Dept of Ophthalmology Ludwig-Maximilians University Muenchen Germany
  • AJ Mueller
    Dept of Ophthalmology Ludwig-Maximilians University Muenchen Germany
  • U Welge-Lüßen
    Dept of Ophthalmology Ludwig-Maximilians University Muenchen Germany
  • Footnotes
    Commercial Relationships   A.S. Neubauer, None; S.G. Priglinger, None; C. May, None; C.S. Alge, None; K. Ludwig, None; A.J. Mueller, None; U. Welge-Lüßen, None.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 160. doi:
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    • Get Citation

      AS Neubauer, SG Priglinger, C-A May, CS Alge, K Ludwig, AJ Mueller, U Welge-Lüßen; Optical Coherence Tomography (OCT) for the Detection of Laser in Situ Keratomileusis (LASIK) in Donor Corneas . Invest. Ophthalmol. Vis. Sci. 2002;43(13):160.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: In the year 2001, more than one million laser in situ keratomileusis (LASIK) procedures have been performed in the United States. Considering the long term collective accumulation of individuals who will have undergone refractive procedures, eye banks will be increasingly confronted with the problem of how to identify those donors with prior refractive surgery. Until now, efficient screening methods to identify excimer laser vision correction surgery in donor eyes have not been established. Thus the purpose of the present study is to determine if Optical Coherence Tomography (OCT) can be utilized to detect the presence of LASIK - induced changes in human corneas. Methods:: LASIK was performed on 20 organ cultured human cornea discs. The excimer laser ablation performed ranged from 0 - 12 diopters. The corneas were maintained in culture, and structural changes were measured with OCT on day 1, 2, 7, 14 and 1, 2, 4, and 6 months after the LASIK procedure. Results: OCT scans were able to detect the interface between the corneal flap and the residual stromal tissue in all corneas and at all examined time intervals. There were no differences in signal intensity among the different ablations depths. The relative intensity compared to averaged stromal intensity ranged from 2.1 - 6.8. Conclusion: Examination of corneoscleral discs by OCT appears to be an appropriate technique for eye banks to screen donor corneas for prior LASIK surgery.

Keywords: 548 refractive surgery: LASIK • 370 cornea: basic science • 607 transplantation 
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