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H Ishikawa, S Piette, JM Liebmann, R Ritch; Mapping Retinal Nerve Fiber Layer Thickness and Internal Reflectivity to the Visual Field . Invest. Ophthalmol. Vis. Sci. 2002;43(13):251.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To assess sector peripapillary OCT information usinga visual field mapping system on correlation of retinal nervefiber layer (RNFL) measurements and visual function.Methods:OCT (Zeiss-Humphrey Systems Inc., Dublin, CA) was used to assessthe peripapillary RNFL in normal and glaucomatous eyes. Circularscan data were divided into 6 sectors based on an achromaticautomated perimeter mapping concept introduced by Garway-Heathet al (Ophthalmology 2000;107:1809-15; see figure).Results:We enrolled 106 eyes of 106 patients (41 normal, 65 glaucoma;mean age 56.1 ± 11.9 (SD) years (range 24 to 78 yrs.)).Mean RNFL index of each sector showed significant correlationwith sensitivity of the corresponding visual field area (p<0.0001,Spearman's rank correlation; see table). Combined mean RNFLthickness of areas 2 and 4 showed the best correlation withMD and CPSD among all combinations of quadrants or clock hoursectors (rs=0.76 (MD), -0.73(CPSD)).Conclusion: The proposedsector analysis may be more suitable for glaucoma assessmentthan the conventional OCT RNFL analysis. These data suggestthat use of arc scan rather than circular scan data is desirablefor evaluating glaucomatous RNFL. Table View OriginalDownload SlideView OriginalDownload Slide View OriginalDownload SlideView OriginalDownload Slide
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