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NJ Reus, TP Colen, PG H Mulder, HG Lemij; Reproducibility of the HRT at 10º and 15º Viewing Angles . Invest. Ophthalmol. Vis. Sci. 2002;43(13):259.
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Purpose: Studies of measurements with the Heidelberg Retina Tomograph (HRT) at both 10º and 15º viewing angles have been published. The reproducibility of measurements at 10º has been reported extensively, whereas the reproducibility at 15º has not been investigated. We assessed the reproducibility of the HRT at both 10º and 15º in healthy subjects and glaucoma patients. Methods: One randomly selected eye per subject of 14 healthy individuals and 15 glaucoma patients was measured on 3 separate days in a 5-week period with the HRT I (software version 2.01; Heidelberg Engineering GmbH, Dossenheim, Germany). For each session, a mean of 3 high quality images was obtained at both 15º and 10º viewing angles. Contour lines were drawn by one operator, for each viewing angle separately, on a single image of the first session at the inner edge of Elschnig's ring with the use of stereoscopic photographs of the optic nerve head. Contour lines were then exported to the mean images, which were used for analysis. Reproducibility was assessed as the limits of agreement (LA; the 95% range for the difference between two measurements in one individual) and as the intraclass correlation coefficient (ICC) for all 11 parameters that are on the print-out. Results: The reproducibility of measurements varied considerably across parameters. Rim Area, Maximum Cup Depth, Mean Cup Depth, and Cup Area had the highest reproducibility as expressed in LA. There was, in general, no significant difference in reproducibility between 10º and 15º scans in both healthy subjects and glaucoma patients, nor was there a difference between groups. The ICC was greater than 90% in all parameters for both groups. Conclusion: The reproducibility of HRT parameters is similar for 10º and 15º scans; it is moderate to high in healthy subjects and in glaucoma patients, with no significant difference between the two groups. CR: N Support: The Rotterdam Eye Hospital Research Fund.
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