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HR Katz, R Adler; The Use of Single-Piece Acrylic Intra-Ocular Lenses to Reduce Post-Operative Complications . Invest. Ophthalmol. Vis. Sci. 2002;43(13):414.
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Purpose: Posterior capsular opacification is a well-known post-operative complication of intra-ocular (IOL) lens placement. Additionally, post-operative inflammation and alterations in refractive stability can undermine desired post-operative outcomes. The single-piece acrylic IOL was developed to reduce these post-operative complications. This study evaluates the incidence of such post-operative complications following implantation of the single-piece lens. Methods: This investigation involves a retrospective analysis of 100 patients who received implantation of a single-piece acrylic IOL (Acrysof, SA30AL and SA60AT, Alcon Laboratories, Fort Worth, Texas) between April 2000 and November 2000. The incidence of visually significant PCO, persistent intraocular inflammation, stability of refraction and stability of IOL position over a period of one year was examined. Results: Early results suggest a reduction in the incidence of PCO, as well as post-operative inflammatory complications and IOL decentration. The low incidence of Nd:YAG capsulotomy rates for the SA30AL and SA60AT lens indicates the reduction of visually significant PCO, and the low frequency of post-operative inflammatory responses suggests a high-degree of bio-compatibility. Additionally, the stability of post-operative refractions suggests excellent centration of the lens in the capsular bag. Conclusion: A low incidence of post-operative complications, such as visually significant PCO, inflammation, and refractive de-stabilization after implantation of the AcrySof single-piece acrylic lens, demonstrates the capacity of these IOLs to maximize desired post-operative outcomes. A theoretical basis for the beneficial effects of these lenses with regard to remaining stable, promoting minimal inflammation and promoting little proliferation of lens epithelial cell across the posterior capsule, will be discussed.
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