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N Villate, V Cruz-Villegas, HW Flynn, PJ Rosenfeld; Severe Vision Decrease within One Week following Photodynamic Therapy . Invest. Ophthalmol. Vis. Sci. 2002;43(13):609.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To evaluate the incidence and outcomes of patients experiencing severe vision decrease (SVD) within one week after photodynamic therapy (PDT). Methods: A retrospective, non-comparative case series. Results: Four patients (0.5%) out of 809 experienced SVD, defined as a 20-letter vision loss within 7 days of treatment. Within 3 months, 3 of the 4 patients recovered vision to less than 20-letter vision loss. Two of the 4 patients recovered their pretreatment visual acuity. The mechanisms for SVD are probable choroidal non-perfusion (2) and submacular hemorrhage (2). Conclusion: SVD is an uncommon event following PDT but vision often improves during follow up.
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