December 2002
Volume 43, Issue 13
Free
ARVO Annual Meeting Abstract  |   December 2002
The Effects of Myopic Disc Changes on Retinal Nerve Fiber Layer Thickness in Normal and Glaucomatous Eyes
Author Affiliations & Notes
  • A Kanamori
    Ophthalmology Kobe Univ Sch of Med Kobe Japan
  • R Seya
    Ophthalmology Kobe Univ Sch of Med Kobe Japan
  • Y Nakasuji
    Ophthalmology Kobe Univ Sch of Med Kobe Japan
  • A Eno
    Ophthalmology Kobe Univ Sch of Med Kobe Japan
  • H Maeda
    Ophthalmology Kobe Univ Sch of Med Kobe Japan
  • M Nakamura
    Ophthalmology Kobe Univ Sch of Med Kobe Japan
  • A Negi
    Ophthalmology Kobe Univ Sch of Med Kobe Japan
  • Footnotes
    Commercial Relationships   A. Kanamori, None; R. Seya, None; Y. Nakasuji, None; A. Eno, None; H. Maeda, None; M. Nakamura, None; A. Negi, None.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 1003. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      A Kanamori, R Seya, Y Nakasuji, A Eno, H Maeda, M Nakamura, A Negi; The Effects of Myopic Disc Changes on Retinal Nerve Fiber Layer Thickness in Normal and Glaucomatous Eyes . Invest. Ophthalmol. Vis. Sci. 2002;43(13):1003.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose:To compare effects of myopic disc changes on retinal nerve fiber layer thickness (RNFL) in normal eyes and in eyes with early open angle glaucoma (OAG) . Methods:Enrolled were 105 control eyes and 77 eyes with early OAG. Myopic disc changes were observed in 34 eyes in the former and in 35 in the latter. The RNFL thickness was measured using Optical Coherence Tomography (OCT), and then subdivided into 12 segments. The RNFL thickness of each segment (S-RNFL-T) were calculated. The receiver operating characteristic curves (ROC) were plotted for each S-RNFL-T of glaucomatous eyes with and without myopic disc changes, on which sensitivity and false positive rate were determined by the mean deviation in the Humphrey Field Analyzer. Percent reduction of each S-RNFL-T in the OAG eyes relative to the control eyes was also calculated. A segment with the highest percent reduction in each individual was determined and the distribution of such a segment was compared between the OAG eyes with myopic disc changes and those without myopic disc changes. Results:In normal eyes, the average of each S-RNFL-T was not different between in those with and without myopic disc changes. The largest area under ROC in the OAG eyes with myopic disc changes was exhibited for inferior temporally segment thickness (93.3), while for inferior segment thickness without myopic changes (92.7). As for the distribution of segments with the highest percent reduction, the inferior temporally segment was the most frequent in the OAG eyes with myopic disc changes (48%), whereas there was no predilection in the distribution in those without myopic disc changes. Conclusion:Myopic disc changes were correlated with the reduction in the retinal nerve fiber thickness at the inferior area in early glaucomatous eyes.

Keywords: 484 nerve fiber layer • 432 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • 481 myopia 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×