Purchase this article with an account.
SN Appa, AN Safar, W Anderson, AO Edwards; Prospective Case-Control Study of Infrared Fundus Imaging in Subjects at High and Low Genetic Risk for AMD . Invest. Ophthalmol. Vis. Sci. 2002;43(13):1206.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
Purpose: To determine the type and frequency of infrared (IR) reflectance abnormalities in subjects with high and low genetic risk for AMD. Methods: Stereoscopic color and IR fundus imaging were prospectively performed on 23 descendents of patients with AMD and an affected first-degree relative and 19 subjects without a family history of AMD. All subjects were between age 40 to 55 years. Results: Drusen and IR reflectance abnormalities were frequent in both groups, but more common in high-risk subjects. Ten subjects (43.5%) in the high-risk group compared to one (5.3%) in the control group had greater than 20 infrared reflectance abnormalities (p<0.03). Conclusion: Infrared imaging may be useful in identifying young individuals at risk for developing AMD.
This PDF is available to Subscribers Only