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K Karim-Zoda, S Grisanti, P Szurman, K-U Bartz-Schmidt; Anatomical and functional Outcome of Macular Hole Surgery with ILM peeling . Invest. Ophthalmol. Vis. Sci. 2002;43(13):2477.
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Purpose: To report the anatomical and functional outcome of macular hole surgery with internal limiting membrane (ILM) peeling and injection of long-acting gas (C3F8) Methods: We examined prospectively 40 eyes of 40 patients with idiopathic macular hole undergoing vitrectomy, ILM-peeling and fluid-gas exchange and compared the best-corrected visual acuity levels with postoperative features of optical coherence tomography and scanning laser ophthalmoscopy images. Results:The treatment was anatomically successful in 30 of 40 eyes (75%) and 17 of the eyes (42,5%) showed an improvement of at least two Snellen lines. The mean of the retinal thickness was 424 nm (range 300-600nm) preoperatively. Postoperatively the mean of the retinal thickness decreased to 348 nm (range 250-370 nm) in cases with anatomical success (P=0,008, Student t-test). In cases of macular hole closure the mean of the foveal thickness ranged from 80 to 440 nm (the mean 180 nm). In all tested eyes fixation-point was preoperatively paracentral. Postoperatively the fixation-point was central in 62,5%, and paracentral in 37,5%. Conclusion:Successfull closure of macular holes was achieved in 75% of the cases. Tomographic images after macular hole surgery correlated with functional outcomes such as best-corrected visual acuity levels and fixation-point.
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