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M Otani, M Inoue, H Shinoda, T Eshita, S Kitamura; Comparison of Indocyanine Green Efficacy in Surgical Outcome for Idiopathic Macular Hole Surgeries . Invest. Ophthalmol. Vis. Sci. 2002;43(13):2481.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To evaluate the efficacy of indocyanine green (ICG) to identify internal limiting membrane (ILM) in vitreous surgeries for idiopathic macular holes. Methods: We retrospectively reviewed 36 eyes of 32 patients with idiopathic macular hole who underwent vitrectomy with ILM peeling (Jan/1998 through June/2001) w/s ICG, followed more than 6 months. The age was 61±6 years in ICG- group and 64±7 in ICG+ group, respectively. The preoperative visual acuity in logMAR was 0.79 and 0.86. The symptomatic period was 5±7 months and 3±1. The mean hole size was 0.3±0.1DD and 0.3±0.1DD. The duration of face-down position was one week in ICG- group and three days in ICG+ group . The anatomical success rate and the visual outcome were studied. The cases with surgical complications were excluded i.e. PVR in comparison of postoperative visual outcome. Results: Anatomical initial success was obtained in 94.7% of ICG- group and 94.1% in ICG+ group (≷0.01). Visual improvement (≷= two lines) was 93.3% and 84.6% (≷0.01), respectively. The possible phototoxicity (initial whitening retinal edema and later retinal pigmental change with visual field defect) was seen in two cases of ICG+ group which did not improve vision. Conclusion: To visualize ILM using ICG in macular hole surgeries was useful in reduction of face-down position and anatomical success. However, new complications were encountered possibly due to dye toxicity.
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