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CJ Chen, CL Willingham; The Use of Indocyanine Green Angiography as an Adjunct to Fluorescein Angiography in the Diagnosis of Ruptured Retinal Arterial Macroaneurysms . Invest. Ophthalmol. Vis. Sci. 2002;43(13):2550.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To determine the usefulness of Indocyanine Green Angiography (ICG) as an adjunct to Fluorescein Angiography (FA) in diagnosing retinal arterial macroaneurysms associated with pre-retinal, intra-retinal, and subretinal hemorrhages. Methods: Retrospective FA and ICG analysis and chart review Results: 19 of 32 patients with the final diagnosis of retinal arterial macroaneurysms had associated overlying hemorrhages. The correct diagnosis was made with FA alone in 14 of 19 eyes (74%). In 4 of 19 eyes (21%) the FA failed to demonstrate the macroaneurysms, which were only seen with the use of ICG. In 1 of 19 eyes (5.3%) both the FA and ICG failed to show the macroaneurysm. The additional use of ICG showed the macroaneurysm in about 80% of the cases where the FA alone failed. Conclusion: ICG is often helpful in demonstrating macroaneurysms associated with hemorrhages when the FA fails. We recommend that if a hemorrhagic macroaneurysm is suspected, FA should be performed initially. If following FA, the diagnosis is uncertain, we recommend follow-up testing with ICG.
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