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H-K Kou, M-L Kao; Clinicopathological Study of Idiopathic Macular Hole: the Influence of Indocyanine Green Staining . Invest. Ophthalmol. Vis. Sci. 2002;43(13):2604.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To check the clinicopathological correlation of idiopathic macular hole and the influence of indocyanine green (ICG) staining during membrane peeling. Methods: Retrospectively reviewing the cases accepting macular hole surgery from Jan 1999 to Nov 2001. All the patients accepted vitrectomy and membrane, epiretinal membrane (ERM) or internal limiting membrane (ILM), peeling with or without the aid of ICG staining. Results: There were 34 cases, 17 cases in each group. There were 26 specimens for pathology, however, lost 12 specimens. ICG staining doesn't alter the specimen loss rate. In the 14 specimens, 10 had ILM only, 4 had ILM and cellular components under the light microscope examination. The pathological finding is highly corresponding with the clinical finding. Electron microscope also confirmed the finding of light microscope. Conclusion: The pathological finding of specimens harvested from macular hole surgery is strongly compatible with the clinical finding. ICG staining doesn't lessen the specimen loss rate. Specimen processing should be improved to lessen the specimen loss rate.
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