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JL Gottlieb, MS Ip, MJ Feldmann, RE Gangnon; Correlation Between Optical Coherence Tomography and Photographic Measurements of Macular Hole Diameter . Invest. Ophthalmol. Vis. Sci. 2002;43(13):2857.
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Purpose: To investigate the relationship between the diameterof macular holes measured from funduscopic photographs and opticalcoherence tomography (OCT).Method: 31 eyes of 31 patients withmacular holes were studied with both techniques. 29 of thesemacular holes were idiopathic while two were traumatic. A magnifyingreticule (Edmunds Scientific Corporation, Barrington, NJ) wasused to manually measure macular hole size from 30º fundus photographstaken with a Zeiss camera (Carl Zeiss Inc., Jena, Germany).Two retina specialists (MI and JG) independently graded thephotographs. Consensus was reached on all measurements. OCTmeasurements were performed using commercially available equipment(Zeiss Humphrey Systems, Dublin, CA). Cross-hair measurementswere performed with scan lengths ranging from 4-8 mm. The sizeof the macular hole on OCT images was determined by countingthe number of individual A-scans between both the corresponding(1) narrowest horizontal points of the macular hole and (2)an inner retina point of the macular hole estimated to representthe inner retinal "opening" of the macular hole.Result: Intraclasscorrelation coefficients: View OriginalDownload SlideView OriginalDownload SlideMean Difference: View OriginalDownload SlideView OriginalDownload Slide* = nominally significant at 5% levelConclusion:The measurement of the OCT narrowest point more closely correlateswith the smaller macular holes as measured from fundus photographs,while the OCT inner retinal hole diameter more closely correlateswith the larger macular holes measured from fundus photographs.The OCT measurements do not appear to correlate well with macularhole diameters as measured from fundus photographs.
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