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T John, CS Bouchard; Human Amniotic Membrane Transplant In Various Anterior Segment Diseases . Invest. Ophthalmol. Vis. Sci. 2002;43(13):4186.
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Purpose: To report the long-term results of human amniotic membrane transplant (HAMT) in various anterior segment diseases. Methods: Eighty-two HAMT were performed in 69 patients [males=45; average age, 55 yr. (range, 14-91 yr.)]. The average follow-up was 27 (range 0.5-64) months. The preoperative diagnoses included pterygium (23), persistent epithelial defect (19), stem cell deficiency (8), symblepharon (8), tectonic (7), chemical injury (5), exposed Ahmed valve (4), corneal perforation (2), corneo-scleral lesion (CSL) benign (2), corneal pannus/conjunctival fibrosis (2), bullous keratopathy (1), CSL malignant (1). Results: The ocular surfaces were stabilized in all of the conditions, except 3 cases. There were 2 failed HAMT with mild recurrence of the pterygium. One failed corneal perforation requiring a penetrating keratoplasty. Conclusion: Human amniotic membrane transplant provides a useful, alternate surgical method of dealing with various anterior segment diseases. Long-term follow-up demonstrated good ocular surface stability.
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