December 2002
Volume 43, Issue 13
Free
ARVO Annual Meeting Abstract  |   December 2002
Early Diagnosis of Birdshot Choriditis
Author Affiliations & Notes
  • R Neumann
    Aviv Eye Department Maccabi Health Care Services Ramat Hasharon Israel
  • S Krupsky
    Ophthalmology Goldschleger Eye Institute Tel Aviv Israel
  • Footnotes
    Commercial Relationships   R. Neumann, None; S. Krupsky, None.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 4261. doi:
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      R Neumann, S Krupsky; Early Diagnosis of Birdshot Choriditis . Invest. Ophthalmol. Vis. Sci. 2002;43(13):4261.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: The potential role of workup using ICG angiography in eyes with posterior inflammation was assessed. This work evaluates early diagnosis of Birdshot Choroiditis (BSC). BSC may present as bilateral vitreitis while the appearance of the pathognomonic multiple cream colored lesions be delayed for years. Methods: Patients with posterior uveitis answered a medical questionnaire regarding past medical history and underwent complete ocular examination and routine uveitis laboratory workup. Flourescein and ICG angiographies were routinely administered for posterior uveitis with questionable diagnosis. Results: Three patients, two males and one female, ages 30-38 presented with posterior uveitis without clinical or fluorescein angiography (FA) criteria of any specific entity. Retinal lesions typical to BSC were not observed. Medical questionnaire and routine uveitis laboratory workup were not diagnostic. ICGA revealed hypofluorescent oval lesions in the posterior pole that paralleled choroidal veins, a pattern typical to BSC. Accordingly, HLA-A29 was obtained and found positive in all three cases substantiating the diagnosis. Conclusions: Routine ICG angiography in posterior segment inflammation may identify signs of BSC at a stage where clinical pathognomonic signs have not yet developed. Early diagnosis may enable frequent follow-up and subsequent anti-inflammatory therapy adjusted to the level of inflammation. Early proper management may prevent the grave late developments of the disease.

Keywords: 430 imaging/image analysis: clinical • 437 inflammation • 344 chorioretinitis 
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