December 2002
Volume 43, Issue 13
ARVO Annual Meeting Abstract  |   December 2002
Vitrectomy and the Management of Uveitis
Author Affiliations & Notes
  • H Kok
    Dept of Clinical Ophthalmology
    Moorfields Eye Hospital London United Kingdom
  • C Lau
    Dept of Clinical Ophthalmology
    Moorfields Eye Hospital London United Kingdom
  • S Lightman
    Professor and Director Dept of Clinical Ophthalmology
    Moorfields Eye Hospital London United Kingdom
  • Footnotes
    Commercial Relationships   H. Kok, None; C. Lau, None; S. Lightman, None.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 4282. doi:
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      H Kok, C Lau, S Lightman; Vitrectomy and the Management of Uveitis . Invest. Ophthalmol. Vis. Sci. 2002;43(13):4282.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract: : Purpose: To review the diagnosis and outcome of patients with uveitis who have undergone vitrectomy. Methods: Retrospective review of case notes of patients who have undergone vitrectomy in the last 5 years. Patients with post surgical endophthalmitis were excluded. The type of uveitis, indication for surgery, outcome and complications were noted. Results: A total of 53 eyes (47 patients) had vitrectomy. Vitrectomy was primarily performed for one of three reasons: 1.) To treat complications of uveitis (27 eyes/57%); a.) Retinal detachment; b.) Vitreous opacification; c.) Macular traction. 2.) To aid in diagnosis (15 eyes/33%). 3.) To remove infectious foci and introduce antibiotics (all were cases of fungal endophthalmitis 4 eyes/9%). Of the 18 eyes that had vitrectomy for retinal detachment, 4 eyes required repeated surgery and 2 eyes had persistent detachment. All 5 eyes that had cystoid macular oedema from noninfective uveitis prior to vitrectomy for non retinal detachment reasons had resolution of the oedema. Complications of vitrectomy included transient high intraocular pressure, entry site dialysis, and retinal detachment. Visual acuity improved in 17 eyes/375, remained the same in 22 eyes/48%, and decreased in 7 eyes/15% as a result of persistent retinal detachment and chronic maculopathy. Conclusion: Vitrectomy was indicated to treat the complications of uveitis, to provide tissue samples for diagnostic purposes, and to manage endogenous mycosis. Severe complications were rare. Vitrectomy may aid the resolution of cystoid macular oedema.

Keywords: 612 uveitis-clinical/animal model • 353 clinical (human) or epidemiologic studies: outcomes/complications • 628 vitreoretinal surgery 

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