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M Shahidi, M Mori, C Xie, J Song; Optical Section Retinal Imaging And Ocular Aberrations . Invest. Ophthalmol. Vis. Sci. 2002;43(13):4346.
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Purpose: To report an optical system that provides simultaneously an optical section image of the retinal tissue and measurement of ocular aberrations. Methods: A laser beam was expanded and focused to a point on the retina by the optics of the eye. A beam splitter was used to optically divide the light reflected and scattered from the retina, for wavefront sensing and for retinal imaging. The optics of a modified slit lamp biomicroscope were used to form an image of the retina onto a CCD camera. For optical section retinal imaging, a cylindrical lens was placed in the path of the incident laser beam to form a focused line on the retina. Due to the angle between the incident laser and imaging path, an optical section image of the retina was captured. Ocular aberrations were measured using the Shack-Hartmann technique. The wavefront aberration function was estimated by sampling the wavefront with a lenslet array that was placed at a plane conjugate with the pupil of the eye and determining the distortions of the wavefront. The system was tested in model eyes and human eyes. Results: Increased high order aberrations resulted in a broader point spread function and a wider laser line profile across the optical section image. The optical section image was enhanced with deconvolution image processing algorithms, using the simultaneously measured point spread function. Conclusion: The preliminary results demonstrate the influence of ocular aberrations on the resolution and contrast of optical section retinal imaging.
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