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F Jonasson, T Sverrisson, A Arnarsson, E Stefánsson, H Sigurdsson, I Gislason, H Sasaki, K Sasaki, T Peto, AC Bird; The Prevalence of Age-Related Maculopathy in Iceland Reykjavik Eye Study . Invest. Ophthalmol. Vis. Sci. 2002;43(13):4389.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To determine the prevalence of age related maculopathy and age related macular degeneration in a population based random sample of citizens of Reykjavik 50 years and older. Methods: 1045 persons 50 years and older participated in the survey. The pupils were dilated and simultaneous stereo fundus photography was done (Nidek 3D/NM). The classification and grading system followed the guidelines of the International ARM Epidemiological Study Group (Bird et al, Surv Ophthalmol, 39, 367 - 374, 1995). The classification and grading was done at the Reading Centre of Moorfields Eye Hospital, London, England. The grading was done by 2 independent trained graders and 1 ophthalmologist trained in grading all using stereoscopic viewers. All photographs were graded by at least 2 masked observers. Results: There was no statistically significant difference between right and left eyes. We therefore present the results for right eyes only in this abstract. 974 right macular photographs could be evaluated. All changes were greatly age-related. In the 50´s 3.5% of right eyes were found to have intermediate soft drusen 63 - 124 microns, 0.6% to have large soft distinct drusen ≷ 125 micron and 0% had large soft calcified (crystaline) or semisolid drusen, the same figures for the 80´s were 13.1%, 6.6% and 11.5% respectively. 2% had hyperpigmentation in their 50´s and 22.2% in the 80´s and the same figures for hypopigmentation were 2.3% in the 50´s and 9.5% in the 80´s. Geographic atrophy was found in 4.7% of those 70 years and older and no-one younger than 70 years of age was found to have geographic atrophy. Exudative macular degeneration was found in 1% of those 70 years and older none of whom was younger than 70 years of age. Conclusion: The prevalence of geographic atrophy is higher than in most populations.The advanced forms are rarely found before age 75 years.
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