December 2002
Volume 43, Issue 13
Free
ARVO Annual Meeting Abstract  |   December 2002
Antibiotic Susceptibility Pattern of Coagulase-Negative Staphylococci in Patients Undergoing Intraocular Surgery
Author Affiliations & Notes
  • CN Ta
    Ophthalmology Stanford University Stanford CA
  • H Mino de Kaspar
    Ophthalmology Stanford University Stanford CA
  • RT Chang
    Ophthalmology Stanford University Stanford CA
  • EM Shriver
    Ophthalmology Stanford University Stanford CA
  • PR Egbert
    Ophthalmology Stanford University Stanford CA
  • K Singh
    Ophthalmology Stanford University Stanford CA
  • MS Blumenkranz
    Ophthalmology Stanford University Stanford CA
  • Footnotes
    Commercial Relationships    C.N. Ta, Allergan, Inc. F; Santen, Inc. C, R; H. Mino de Kaspar, None; R.T. Chang, None; E.M. Shriver, None; P.R. Egbert, None; K. Singh, None; M.S. Blumenkranz, None. Grant Identification: Edward E. Hills Fund, Department of Ophthalmology, University of LMU, Munich, Germany, and Hannelore
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 4444. doi:
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    • Get Citation

      CN Ta, H Mino de Kaspar, RT Chang, EM Shriver, PR Egbert, K Singh, MS Blumenkranz; Antibiotic Susceptibility Pattern of Coagulase-Negative Staphylococci in Patients Undergoing Intraocular Surgery . Invest. Ophthalmol. Vis. Sci. 2002;43(13):4444.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To determine the antibiotic susceptibility patternof coagulase-negative staphylococci (CNS) in patients undergoinganterior segment intraocular surgery.Methods: Conjunctivalcultures were obtained (prior to application of antibiotic orantiseptic agent) from 66 consecutive patients undergoing intraocularsurgery who consented to this prospective study. All bacteriaisolates were identified and antibiotic susceptibility determinedby Kirby-Bauer disc-diffusion technique.Results: A total of76 CNS were isolated. 

 ABX, antibiotic;S, Sensitive; I, Intermediate; R, Resistant; PCN, penicillin;OX, oxacillin; MET, methicillin; MZ, mezlocillin; CZ, cefazolin;CTX, cefotaxime; CAZ, cetazidime; Cipro, ciprofloxacin; Levo,levofloxacin; Nor, norfloxacin; Oflox, ofloxacin; IPM, imipenem;MER, meropenem; Gent, gentamicin; Tobra, tobramycin; Amik, amikacin;Neo, Neomycin; Eryth, erythromycin; TCN, tetracycline; C, chloramphenicol;Vanco, vancomycin.Conclusions: Coagulase-negative staphylococciisolated from patients undergoing intraocular surgery remainhighly sensitive to all antibiotics tested except for penicillinanalogues, ceftazidime, and erythromycin. This study suggeststhat fluoroquinolones and aminoglycosides are effective prophylacticantibiotics against most coagulase-negative staphylococci. Support:Edward E. Hills Fund, Department of Ophthalmology, Universityof LMU, Munich, Germany, and Hannelore-Georg Zimmerman Foundation,Munich, Germany.

Keywords: 319 antibiotics/antifungals/antiparasitics • 398 endophthalmitis • 365 conjunctiva 
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