September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Fundus autofluorescence in diabetic macular edema as a tool for establishing diagnosis, prognosis and treatment.
Author Affiliations & Notes
  • Ruben de Jesus Medellin-Bulbarela
    Ophthalmology, CIDOCS - UAS, Culiacan, Sinaloa, Mexico
  • David Magana
    Ophthalmology, CIDOCS - UAS, Culiacan, Sinaloa, Mexico
    Buena Vista Sinaloa I.A.P., Culiacan, Mexico
  • Julio Cesar Ceja Aguilar
    Ophthalmology, CIDOCS - UAS, Culiacan, Sinaloa, Mexico
    Buena Vista Sinaloa I.A.P., Culiacan, Mexico
  • Carlos Gerardo Arias Rodriguez
    Ophthalmology, CIDOCS - UAS, Culiacan, Sinaloa, Mexico
  • Cindy Haro Zuno
    Ophthalmology, CIDOCS - UAS, Culiacan, Sinaloa, Mexico
  • Daniela Del Rio Mora
    Ophthalmology, CIDOCS - UAS, Culiacan, Sinaloa, Mexico
  • Efrain Romo-Garcia
    Ophthalmology, CIDOCS - UAS, Culiacan, Sinaloa, Mexico
    Buena Vista Sinaloa I.A.P., Culiacan, Mexico
  • Footnotes
    Commercial Relationships   Ruben Medellin-Bulbarela, None; David Magana, None; Julio Cesar Ceja Aguilar, None; Carlos Arias Rodriguez, None; Cindy Haro Zuno, None; Daniela Del Rio Mora, None; Efrain Romo-Garcia, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 1658. doi:
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    • Get Citation

      Ruben de Jesus Medellin-Bulbarela, David Magana, Julio Cesar Ceja Aguilar, Carlos Gerardo Arias Rodriguez, Cindy Haro Zuno, Daniela Del Rio Mora, Efrain Romo-Garcia; Fundus autofluorescence in diabetic macular edema as a tool for establishing diagnosis, prognosis and treatment.. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1658.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Describe the characteristics of the different patterns of fundus autofluorescence found in patients with diabetic macular edema and correlate these findings with functionality for establishing a definitive diagnosis, prognosis and treatment.

Methods : In this pilot study we’ve included patients diagnosed with diabetic macular edema as seen in fundus evaluation by our retina specialists. Retina imaging was performed including fundus photography, fluorescein angiography, SD-OCT and fundus autofluorescence with the Heidelberg Spectralis OCT (Heidelberg Engineering, Germany). Data were collected for image analysis and comparison was performed paying special attention to the characteristics of each different pattern and functionality, therefore establishing a definitive diagnosis, prognosis and treatment for each patient.

Results : So far the autofluorescence patterns found in the macular area are those with a normal (16.92%), single-spot (1.99%), multiple-spot (53.94%), cystic (21.98%), diffuse (1.29%) or irregular (3.88%) pattern in the foveal avascular zone predominantly and these findings are correlated with the severity of each patient according to OCT and clinical examination.

Conclusions : In fundus autofluorescence we found that patterns described in patients with diabetic macular edema are consistently found and correlated with functionality and severity according to the patterns found in SD-OCT. We found that this study is capable of diagnose patients that course with diabetic macular edema without knowing it while applying the data acquired for establishing a prognosis before deciding a treatment, thus offering an early treatment option according to the severity of each patient.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

 

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