September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Ultrawide-field OCT angiography with a 200kHz swept-source OCT system
Author Affiliations & Notes
  • Gangjun Liu
    Casey Eye Institute, Portland, Oregon, United States
  • Jie Wang
    Casey Eye Institute, Portland, Oregon, United States
  • Miao Zhang
    Casey Eye Institute, Portland, Oregon, United States
  • Yali Jia
    Casey Eye Institute, Portland, Oregon, United States
  • David Huang
    Casey Eye Institute, Portland, Oregon, United States
  • Footnotes
    Commercial Relationships   Gangjun Liu, None; Jie Wang, None; Miao Zhang, None; Yali Jia, Optovue, Inc (F), Optovue, Inc (P); David Huang, Carl Zeiss Meditec, Inc. (P), Optovue, Inc (F), Optovue, Inc (I), Optovue, Inc (P), Optovue, Inc (R)
  • Footnotes
    Support  Supported by Oregon Health & Science Foundation, DP3 DK104397, R01 EY024544, R01 EY023285 and P30 EY010572, and an unrestricted grant from Research to Prevent Blindness.
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 442. doi:
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    • Get Citation

      Gangjun Liu, Jie Wang, Miao Zhang, Yali Jia, David Huang; Ultrawide-field OCT angiography with a 200kHz swept-source OCT system. Invest. Ophthalmol. Vis. Sci. 2016;57(12):442.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To demonstrate high-definition wide-field angiographic imaging of the human retina.

Methods : : A 200 kHz swept-source OCT system was developed using a tunable laser (Axsun, Inc.) operating at 1044 nm central wavelength. The laser has a tuning range of 104 nm, which provided an axial resolution of 5.7 microns full-width-half-maximum in tissue. The sample arm included a slit-lamp base, a chin rest, an iris camera, a pico-projector fixation target, and an electrically tunable lens for rapid focusing. The k-clock frequency was electronically doubled to increase the axial imaging range from 3.5 mm to 7.0 mm. A split-spectrum algorithm that combines both phase and amplitude information was used for angiographic calculation.

Results : Using only 2 B-frames at each location, high-definition (10~15 micron sampling interval) OCT angiography could be captured over 8x8mm or 10x6mm areas in 4 seconds. By montaging four 10x6mm scans, an ultrawide-field OCT angiography with 10x21 mm (35x70°) field of view was demonstrated (Fig. 1). The scan location was controlled by moving the fixation target using the pico-projector. The total imaging time for ultrawide field of view can be accomplished in 15 minutes.

Conclusions : By using a highly efficient angiography algorithm and a fast OCT system, wide-field OCT angiography could be achieved without sacrificing sampling density or extending acquisition time. Ultrawide field of view can be realized by montaging a few wide-field scans.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

 

An ultrawide-field OCT angiography with 10x21 mm (35x70°) field of view. The angiographic image was obtained by montaging four 10x6mm (800 x 400 points) scans.

An ultrawide-field OCT angiography with 10x21 mm (35x70°) field of view. The angiographic image was obtained by montaging four 10x6mm (800 x 400 points) scans.

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