September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Speckle-noise free choroidal angiography and vessel surface area measurement with Spectral OCT
Author Affiliations & Notes
  • Peter Maloca
    Ophthalmology OCTlab, University of Basel, Basel, Switzerland
  • Footnotes
    Commercial Relationships   Peter Maloca, Heidelberg (F), Peter Maloca (P), Roche (C), Topcon (C), Zeiss (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 455. doi:
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    • Get Citation

      Peter Maloca; Speckle-noise free choroidal angiography and vessel surface area measurement with Spectral OCT. Invest. Ophthalmol. Vis. Sci. 2016;57(12):455.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Approximately 95% of the ocular blood flow is directed to the uveal system, of which approximately 70% is circulating into the choroidal vessels. We visualize these vessels and measure their surface with speckle-noise freed 3D optical coherence tomography.

Methods : 3DOCT volumes were obtained from 20 healthy eyes (10 females) with Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany). The scan pattern was raster lines 4.5x3.0x1.9 mm, 261 B-Scans, with EDI-mode on, averaged for 20 scans using the automatic averaging and tracking tool. The OCT volumes were freed from speckle-noise with a prototype denoising analysis software. Choroidal vessels were segmented and their total surface area was calculated.

Results : 20 eyes of healthy females were investigated. The mean central choroidal vessel surface area was 0.18444301 mm2 (range 0.154483253 mm2 - 0.215696694 mm2; SD 0.01882505). Three dimensional models of the choroidal vessels were reconstructed.

Conclusions : Speckle-noise free chororoidal angiography and surface measurement may be a potential complementary 3D visualization technology for choroidal vessels.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

 

Speckle-noise free 3DOCT angiography of choroidal vessels.

Speckle-noise free 3DOCT angiography of choroidal vessels.

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